6-Bromo-7-methoxy-1,1-dimethyl-3,4-dihydronaphthalen-2(1H)-otu

Ọdịdị kemịkalụ

6-Bromo-7-methoxy-1,1-dimethyl-3,4-dihydronaphthalen-2(1H)-otu bụ mmiri doro anya nke na-enweghị agba ruo na odo dị nro, nke a naghị agbaze na mmiri, nke a na-agbaze na CHCl₃, e kwesịrị ịchekwa ya n'ime friji, kewapụ ya na ihe ndị na-eme ka oxidant dị, kemịkalụ a na-eri eri, pụọ na ọkụ, ebe ọkụ na-esi.

Ngwa

6-Bromo-7-methoxy-1,1-dimethyl-3,4-dihydronaphthalen-2(1H)-otubụ ihe na-egbochi Alectinib, ihe na-egbochi lymphoma kinase (ALK) nke nwere ike ịhọrọ nke ọma ma sie ike nke nwere ike igbochi ihe na-egbochi onye na-echebe ọnụ ụzọ ámá, nke na-ebute mbelata uto mkpụrụ ndụ.

Ụdị anụ ahụ

Mmiri mmiri na-acha odo odo ruo na-acha agba odo

Ndụ nchekwa

Dịka ahụmịhe anyị si dị, enwere ike ịchekwa ngwaahịa ahụ maka awa 12.ọnwa site na ụbọchị ebuga ya ma ọ bụrụ na edobere ya n'ime akpa mechiri emechi, chebe ya pụọ ​​na ìhè na okpomọkụ ma chekwaa ya na okpomọkụ dị n'etiti 5 -30°C.

TNjirimara ypical

Isi Mmiri

354.7±42.0°C na 760 mmHg

Ebe mgbari

168.3±27.9°C

Nzube kpọmkwem

282.025543

PSA

26.30000

Ndekọ

3.25

Nrụgide Uzuoku

0.0±0.8 mmHg na 25°C

Ndepụta nke Refraction

1.545

pka

1.26±0.10 (Amụma)

Mmiri na-agbaze

50 mg/ml na CHCl₃